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Pituitary microadenoma with prolactin, corticotropic and thyreotropic deficiency: from infertility to pregnancy : About a case.

Diallo Moussa, Koulimaya Cyr Esperence Gombet, Diallo Astou Coly Niassy, Diouf Abdoul Aziz, Gassama Omar, Gueye Mame Diarra Ndiaye, Leye Yakham, Diouf Alassane

DOI: 10.5455/IJMRCR.pituitary-microadenoma

Int J Med Rev Case Rep. 2017; 1(1): 17-19

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What we can learn from this publication?

It presents a case of 36-year-old woman, nulliparous, with galactorrhoea without amenorrhea, and primary infertility of the unexplored 10-year-old couple. Authors showed a delay in ideation, pubic and axillary depilation and bilateral galactorrhea. Examination of the thyroid gland found a homogeneous goitre without clinical sign of hypothyroidism. There was no evidence of intracranial hypertension. The patient had a body mass index of 27.04. The thyroxine (tetraiodothyronine) level was decreased to 9.96 pmol / L, a level of thyrotropin releasing hormone (usTSH) normal to 1.689 uUI / ml, a prolactin level of 45.42 ng/ml and a cortisol level of 78 ng/ml. Thyroid ultrasound noted a moderate left lobe heteronodular goitre. Pituitary magnetic resonance (MRI) imaging with gadolinium injection resulted in a 5.5 mm left microadenoma with delayed contrast enhancement compared to the rest of the gland. In summary, the diagnosis of pituitary prolactin’s microadenoma was retained with corticotropic and thyrotropic insufficiency complicated by primary infertility. She had subsequently benefited from a cabergoline-based treatment. Nineteen months later, the patient, with very irregular follow-up, was admitted to maternity for the management of a pregnancy.

This publication describes the management of pituitary microadenomas, its diagnostics and treatment regimes.


References:

  1. Fatfouta I, Delotte J, Mialon O, Isnard V, Bongain A. Adenome a prolactine : du desir de grossesse a l’ accouchement. journal de gynecologie obstetrique et biologie de la reproduction 2013;42:316—24.
  2. Molitch ME. Pituitary Diseases in Pregnancy. Seminars in perinatology. 1998;22(6):457-70.
  3. Sunita MC, Sousa D, Peter E, Ann IM. Pituitary hyperplasia: case series and literature review of an underrecognised and heterogeneous condition.
    Endocrinology, Diabete and Metabolism cases report May 2015 D: 15-0017 DOI: 10.1530/EDM-15-0017.
  4. Melmed S, Casanueva F, Hoffman A. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab; 2011;96:273—88.
  5. Casanueva F, Molitch M, Schlechte J. Guidelines of the Pituitary Society for the diagnosis and management of prolactinomas. Clin Endocrinol. 2006;65:265—73.
  6. Soto-Ares G, Cortet-Rudelli C, C D, JP P. Adenomes hypophysaires et grossesse: considerations morphologiques en IRM. Journal de radiologie. 2002;83:329-35.
  7. Bonneville J-F, Cattin F, Bonneville F. Imagerie desadenomes hypophysaires. Encyclopedie medico-chirurgicale Elsevier Masson SAS; 2009. p. 84-91.
  8. Delemer B. Adenomes a prolactine : diagnostic et prise en charge. Presse Medicale. 2009;38:117-25.
  9. Molitch M. Prolactin-secreting tumors: what’s new? . Expert Rev Anticancer Ther. 2006;6:S29—35

How to Cite This Article

Moussa D, Gombet K, Niassy D, Aziz D, Omar G, Ndiaye G, et al. Pituitary microadenoma with prolactin, corticotropic and thyreotropic deficiency: from infertility to pregnancy : About a case. International Journal of  Medical Reviews and Case Reports [Internet]. ScopeMed International Medical Journal Management and Indexing System; 2017;1. Available from: http://dx.doi.org/10.5455/ijmrcr.pituitary-microadenoma

Last modified onSaturday, 09 November 2019 13:11